Synacinn™: Bacterial reverse mutation test data in five histidine-requiring strains of Salmonella Typhimurium
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منابع مشابه
HISTIDINE MUTANTS REQUIRING ADENINE: SELECTION OF MUTANTS WITH REDUCED hisG EXPRESSION IN SALMONELLA TYPHIMURIUM H
A method is described for the selection of Salmonella typhimurium mutants with reduced levels of hisG enzyme activity. This method is based on the fact that the hisG enzyme catalyzes the consumption of ATP in the first step of histidine biosynthesis. Normally, this reaction is closely regulated, both by feedback inhibition and by repression of the operon. However, conditions can be set up that ...
متن کاملHistidine mutants requiring adenine: selection of mutants with reduced hisG expression in Salmonella typhimurium.
A method is described for the selection of Salmonella typhimurium mutants with reduced levels of hisG enzyme activity. This method is based on the fact that the hisG enzyme catalyzes the consumption of ATP in the first step of histidine biosynthesis. Normally, this reaction is closely regulated, both by feedback inhibition and by repression of the operon. However, conditions can be set up that ...
متن کاملHistidine Regulatory Mutants in Salmonella typhimurium
Regulation of the histidine operon in Salmonella typhimurium has been shown to involve at least six separate genes (Roth, Antdn & Hartman, 1966; Ant&, 1968). Mutations in any one of these separate genes can destroy the ability of the cell to repress fully the histidine biosynthetic enzymes. In order to understand this regulatory mechanism and the nature of these mutations, we have studied the d...
متن کاملIsoleucine - Valine Requiring Mutants of Salmonella Typhimurium
E have isolated a number of mutant strains of Salmonella typhimurium that display a marked inhibition of growth when valine is added to minimal medium. Attempts to elucidate the nature of the mutation(s) in these valinesensitive strains have included enzymatic and transductional analyses, as well as growth studies, on four of these strains. The results of these studies are presented and discuss...
متن کاملIsoleucine-valine Requiring Mutants of Salmonella Typhimurium.
initial reports on the mutant strains of Salmonella typhimurium that T: eui r both isoleucine and valine for growth (ilva strains) were published concomitantly by GLANVILLE and DEMEREC ( 1960) and WAGNER and BERGQUIST (1960). These studies showed that although the available ilva strains could be divided into four complementation groups ( A , B , C and D ) on the basis of abortive transduction r...
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ژورنال
عنوان ژورنال: Data in Brief
سال: 2021
ISSN: 2352-3409
DOI: 10.1016/j.dib.2021.107075